When I tried Microsoft’s Mesh a few years back I thought it had great potential. But it wasn’t clear what Microsoft was going to do with the software. Since that time, I have been using Dropbox; which has an elegant simplicity (and works across different platforms).
Moreover, I didn’t even realize that “Mesh” is now Live Mesh and is included with Windows Live Essentials (since September 30, 2010). Windows Live Essentials are very nice tools (which Microsoft does not market well). Heck, if I’d known Live Mesh was available I might not have tried Dropbox—but I am glad I did.